We report a case of hccc socalled ccc nos referred to as hccc of the minor salivary gland of the buccal mucosa. Lesions in this location may stem from cheek biting that results in frictional hyperkeratosis, irritation fibroma, irritation from medications such as aspirin or lichen planus however. To evaluate the role of serial cytological assay in calculating the nuclear response of contralateral normal buccal mucosa and peritumoural area of squamous cell carcinoma of oral cavity in patients receiving fractionated radiotherapy rt and chemotherapy. Pdf verrucous carcinoma of the buccal mucosa a case report. In the indian male anaplastic carcinoma affected the buccal mucosa, palate. It is a brighter red, smooth, and shiny with many blood vessels, and is not connected to. Carcinoma buccal mucosa anatomy to management slideshare. Squamous cell carcinoma scc of the buccal mucosa is associated with a poor prognosis because of the high incidence of recurrent disease. Presence of palpable fibrous bands in the buccal mucosa, retromolar areas and rimaoris. Curative radiotherapy for early cancers of the lip, buccal. This cancer occurs preferentially in the tongue, buccal mucosa and gingiva. The clinical characteristics of benign oral mucosal tumors.
After 1 week of the onset of pain, the patient noticed a small swelling in the left buccal mucosa. Pdf squamous cell carcinoma of the buccal mucosa involving the. Adenosquamous carcinoma is a rare malignant tumor with poor prognosis that is characterized histopathologically by the simultaneous presence of distinct areas of adenocarcinoma and squamous cell carcinoma. Until 2004, only 59 cases of adenosquamous carcinoma have been documented in english literatures in the head and neck region since the first one being reported in 1968. Normal oral mucosal keratinocytes are chronically exposed to risk factors, which can break the. Carcinoma of the buccal mucosa is relatively uncommon in north america, compared with other oral cavity cancers such as carcinomas of the tongue or floor of the mouth. The peculiarity of the lesion and the approach we made is the key factor in the presentation. Regional centre for cancer research and treatment, orissa, india. Adenoid cystic carcinoma is a malignant neoplasm most commonly originating in salivary glands of head and neck region. The buccal mucosa is a rare location for oral cancer, as this site is involved in approximately 10% of oral cancer cases diagnosed in the united states.
The patient gave a history of tobacco chewing since 38 years. Inner cheek cancer also called buccal mucosa cancer is a type of head and neck cancer that begins when the cells that make up the inner cheek grow out of control and form lesions or tumors. The first reported case in the buccal mucosa is in 2009 8. Anatomy the buccal mucosa includes the mucosal surfaces of the cheek and lips from the line of contact of the opposing lips to the pterygomandibular raphe posteriorly. Carcinoma of buccal mucosa is a type of oral cancer or mouth cancer. The buccal mucosa includes the mucosal surfaces of the cheek and lips from the line of contact of the opposing lips to the pterygomandibular raphe posteriorly. Despite current progress in various treatment modalities, over the past 50 years survival rates have not improved drastically. In the asian indian population the high incidence of buccal carcinoma is believed to stem from the highly prevalent habit of chewing betel nut. Whule surgery went well, lymph nodes came negative and margin of tissue removed from cheek also came negative, i do have questions on post operative recovery aspects. However, the biopsy showed early squamous cell carcinoma. Squamous cell carcinoma of the buccal mucosa sciencedirect. The authors received no specific funding for this work.
Squamous cell carcinoma scc of the buccal mucosa is a common malignant tumor in the chinese mainland, taiwan and india. Addressing squamous cell carcinoma of the buccal mucosa. Squamous cell carcinoma of the buccal mucosa has an aggressive nature, as it grows rapidly and penetrates well with a high recurrence rate. Bilateral squamous cell carcinoma of buccal mucosa in a young. Alveolar mucosa, the lining between the buccal and labial mucosae. Mucinous adenocarcinoma is very rare, and is commonly seen in elderly males. Squamous papilloma of the buccal mucosa with oral submucous fibrosis. Twelve of the tumours were staged as t1 or t2 tumours. Pdf profile of buccal mucosa carcinoma patients in regional.
Fibrosarcoma of the oral cavity wadhwan v, chaudhary ms. Oral potentially malignant disorders opmd often precede squamous cell carcinoma. Kaposi sarcoma is a malignat vascular tumor that may arise in multiple sites. Risk factors associated with scc include betel quid chewing, tobacco and alcohol consumption 1 3. Apart from squamous cell carcinoma, the commonest oral cancer is mucoepidermoid cancer arising out of the minor salivary glands. Postoperative radiotherapy in carcinoma of buccal mucosa, a prospective randomized trial. Introduction the anatomy of the buccal mucosa and buccal space allows for extension of carcinoma unimpeded by any.
Introduction granular cell tumor gct or abrikosoffs tumor was firstly described in 1926 and it is a rare benign soft tissue lesion that can occur in any part of the body, but over. Characteristics of oral squamous cell carcinoma in users or. In the indian female anaplastic carcinoma occurred most commonly on the buccal mucosa. Adenoid cystic carcinoma of buccal mucosa springerlink.
This article documents the process that led to the publication of the oral cis jsop catalog by the working committee on new histopathological criteria for. A 52yearold woman had presented with a gradually growing and indolent mass in the right buccal mucosa. Carcinoma buccal mucosa oral mucosa carcinoma causes. Oral granular cell tumor in a brazilian population. Treatment of oral cancer poses unique reconstructive challenges, owing to the dynamic architecture of the oral cavity. The disease is treated with surgery, chemotherapy or both. If so, then the experience would be more like those of us with tonsillectomies or other oral surgery. Available data suggest that recurrent disease is most often locoregional, with distant metastases affecting a relatively small number of patients. Squamous cell carcinomas arising in this area are usually well differentiated and are frequently associated with areas of leukoplakia. On palpation the lesion was soft in consistency, nontender, with smooth borders and was pulsatile in nature.
We are referred a large number of locally advanced lesions. The control of oral squamous cell carcinoma scc is difficult even after treatment because it has a tendency to multiple primary carcinomas. Rajendar prasad government medical college rpgmc tanda, him achal pradesh, india abstract buccal mucosal swellings are more often noticed in day to day practi ce. I also was diagnosed with buccal mucosa cancer right cheek. Nicotine is rapidly absorbed through the oral cavity mucosa or pulmonary. The incidence of buccal mucosa carcinoma has rapidly increased in taiwan in recent decades. Unusual occurrences of this neoplasm are reported in hard palate, maxillary sinuses, lip, etc. Acknowledgement this article could not have been possible without the help of the staffs of the department of oral and maxillofacial pathology, r. Here we present a case report of a 50 year old male who was diagnosed with adenoid cystic carcinoma of the right buccal mucosa. Naik r, nithin kp, mujib br, rai kk 2014 an unusual presentation of squamous papilloma on the buccal mucosa. The buccal mucosa is the lining of the cheeks and the back of the lips, inside the mouth where they touch the teeth. Oral mucosa can be divided into three main categories based on function and histology.
However, buccal mucosa buccal means mouth or, more specifically, cheek would be gotten to from the inside, no. Pdf squamous cell carcinoma of the buccal mucosa has an aggressive nature, as it grows rapidly and penetrates well with a high recurrence rate. Buccal mucosa also see nccn guidelines for oral cavity cancers, early, advanced, most advanced and dose recommendations. The majority had squamous cell carcinoma scc, one patient had mucoepidermoid carcinoma, and another an alveolar softpart sarcoma of the buccal mucosa. Squamous cell carcinoma is the most common pathology and more prevalent in those who use tobacco and alcohol. We report a case of adenoid cystic of buccal mucosa in a 40year old female.
Oral cavity squamous cell carcinoma an overview longdom. Oral mucosal disease or lesion depends upon creating a differential diagnosis. Lining mucosa, nonkeratinized stratified squamous epithelium, found almost everywhere else in the oral cavity, including the. The fibroma is the most frequent benign tumor of the oral cavity.
Melanocarcinoma of the buccal mucosa sciencedirect. Case discussion biopsy proven case of squamous cell carcinoma in right buccal mucosa. The use of tobacco and alcohol makes cancer in this area far more likely. Aims of reconstruction reconstruction after oral cancer resections should aim.
The incidence varies from 40% to 60% of all cancers of the head and neck in south asia to about 10% in north america and western europe. Squamous cell carcinoma of the buccal mucosa involving the. The lesion is suspicious because of the presence of nodules. The oral cavity includes the lips, hard palate the bony front portion of the roof of the mouth, soft palate the muscular back portion of the roof of the mouth, retromolar trigone the area behind the wisdom teeth, front twothirds. The patient was a resident of the vidarbha region of central india. Mucosa ginigva and alveolar buccal irritation fibroma canalicular adenoma 40 years pleomorphic adenoma carcinoma mucocele. Squamous cell carcinoma of the buccal mucosa is a common cancer in india.
Anaplastic squamous cell carcinoma of the mouth a report. Tobacco and alcohol use are considered the major risk factors for buccal carcinoma in the united states. In patients with buccal mucosa carcinoma, locoregional recurrence rate, 3080% is the main cause of treatment failure4, 5. Fluorescence influence on screening decisions for oral malignant. Go here and here for some studies on outcome and treatment. In the malay male anaplastic carcinoma occurredmost frequently on the gingivae.
Hyalinizing clear cell carcinoma hccc, socalled clear cell carcinoma, not otherwise specified ccc nos, of the salivary glands is a rare and lowgrade malignant tumor. Although throughandthrough resection of skin decreased risk of disease recurrence, this difference is not statistically significant p. Several predictive factors for locoregional recurrence have been reported. Minor salivary gland tumors of oral cavity are very rarely encountered in daytoday practice. The staging for the progression of mucosal melanoma is vague because of how rare this type of melanoma is. Routinely they are associated with buccal space, buccal fat pad. That would mean no obvious scars on the outside but lots of painful work inside. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Among intra oral adenoid cystic carcinoma, buccal mucosa is among the rarest sites. These cancers usually occur in the thin, flat cells called squamous cells that line the buccal mucosa and other parts of the mouth.
Adenoid cystic carcinoma of buccal mucosa article pdf available in journal of maxillofacial and oral surgery 93. Squamous cell carcinoma scc of the buccal mucosa is a relatively uncommon cancer that is aggressive and associated with a high rate of recurrence. The squamous papilloma is a common benign oral epithelial neoplasm 1 1. The main reason for this disparity is the use of smokeless tobacco in south asia. This prospective, nonrandomized study was comprised of 76 histologically confirmed cases of oral. In the asian indian population the high incidence of buccal. Acinic cell carcinoma acc is a rare epithelial malignant neoplasm of salivary glands affecting predominantly the female population. Buccal mucosa is another name for the inside lining of the cheeks.
Adenosquamous carcinoma in buccal mucosaa case report. In our clinical practice, we have observed a high incidence of locoregional failure in squamous cell carcinoma scc of the buccal. A model to predict nodal metastasis in patients with oral. Carcinoma of buccal mucosa is the most common cancer of the oral cavity in india. Definition of buccal mucosa nci dictionary of cancer. Squamous cell carcinoma scc of the buccal mucosa is a rare, but especially aggressive, form of oral cavity cancer, associated with a high rate of locoregional recurrence and poor survival. The buccal complex consists of four layers starting with the mucosa, buccinator muscle, subcutaneous tissue, and skin in to out.
This extends to the line of attachment of the mucosa of the upper and lower alveolar ridge superiorly and inferiorly. Heterogenously enhancing mass lesion in the right buccal mucosa with multiple enlarged right level ib lymph nodes. The oral cavity includes the lips, hard palate the bony front portion of the roof of the mouth, soft palate the muscular back portion of the roof of the mouth, retromolar trigone the area behind the wisdom teeth, front twothirds of the tongue, gingiva gums, buccal mucosa the inner lining of the lips and cheeks, and floor of the mouth under the tongue. Following the study of 300 patients histologically diagnosed with benign tumor of the oral mucosa, we can state that with regard to prevalence, we found significant differences with respect to gender, being more frequent in women. Mucoepidermoid carcinoma of buccal mucosa a case report sukhvinder singh rana 1, neera ohri 2 1,2 senior resident, dr. He gave a history of pain in the posterior mandibular region since 4 months. Inner cheek cancer buccal mucosa cancer memorial sloan. Histology shows tumor cells floating in pools of mucin, compartmentalized by fibrous tissue.